Article
Bonus, a Drosophila TIF1 homolog, is a chromatin-associated protein that acts as a modifier of position-effect variegation.
Genetics - 1 Feb 2005
Beckstead R B, Ner S S, Hales K G, Grigliatti T A, Baker B S, Bellen H J
Abstract excerpt
Bonus, a Drosophila TIF1 homolog, is a nuclear receptor cofactor required for viability, molting, and numerous morphological events. Here we establish a role for Bonus in the modulation of chromatin structure. We show that weak loss-of-function alleles of bonus have a more deleterious effect on m...
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