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Article

cysB and cysE mutants of Escherichia coli K12 show increased resistance to novobiocin.

Molecular & general genetics : MGG - 1 Aug 1991

Rakonjac J, Milic M, Savic D J

Abstract excerpt

Mutations in the cysB and cysE genes of Escherichia coli K12 cause an increase in resistance to the gyrase inhibitor novobiocin but not to coumermycin, acriflavine and rifampicin. This unusual relationship was also observed among spontaneous novobiocin resistant (Novr) mutants: 10% of Novr mutants isolated on rich (LA) plates with novobiocin could not grow on minimal plates, and among those approximately half...

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Source

Identifiers

PMID: 1886615
DOI: 10.1007/BF00282481

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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cysB and cysE mutants of Escherichia coli K12 show increased resistance to novobiocin.PMID 1886615Read ↗

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Genetic structure and regulation of the cysG gene in Salmonella typhimurium.Semantic proximity Read ↗

Alternative pathways for siroheme synthesis in Klebsiella aerogenes.Semantic proximity Read ↗

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