Article
Identification of the CysB-regulated gene, hslJ, related to the Escherichia coli novobiocin resistance phenotype.
FEMS microbiology letters - 29 Jul 2003
Lilic Mirjana, Jovanovic Milija, Jovanovic Goran, Savic Dragutin J
Abstract excerpt
The cysB gene product is a LysR-type regulatory protein required for expression of the cys regulon. cysB mutants of Escherichia coli and Salmonella, along with being auxotrophs for the cysteine, exhibit increased resistance to the antibiotics novobiocin (Nov) and mecillinam. In this work, by using lambdaplacMu9 insertions creating random lacZ fusions, we identify a gene, hslJ, whose expression appeared to be...
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