Involvement of cysB and cysE genes in the sensitivity of Salmonella typhimurium to mecillinam.

Abstract excerpt

cysB and cysE strains were obtained as spontaneous mecillinam-resistant mutants of Salmonella typhimurium. The resistance to mecillinam was caused by the cys mutations which also conferred tolerance to lethal cell shape mutations. Most, but not all, cysB and cysE mutations from other origins disp...

Topics

• Acetyltransferases
• Amdinocillin
• Bacterial Proteins
• Cysteine
• Drug Resistance, Microbial
• Escherichia coli Proteins
• Gene Expression Regulation, Bacterial
• Genes, Bacterial
• Mutation
• Regulon
• Salmonella typhimurium
• Serine
• Serine O-Acetyltransferase
• Sulfides
• Sulfites
• Thiosulfates