Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alternative expression of TCRζ related genes in patients with chronic myeloid leukemia

1 Dec 2012

Abstract excerpt

A previous study has demonstrated a significant decrease in the TCRζ gene expression level in chronic myeloid leukemia (CML); thus, we further investigated the expression of TCRζ-regulating factors, the distribution of the TCRζ 3' untranslated region (3'-UTR) splice variants, and the expression level and correlation of the alternative splicing factor/splicing factor 2 (ASF/SF-2), FcεRIγ and ZAP-70 genes. TCRζ...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chronic Myeloid Leukemia Treatments
Share to Cytokine Signaling Pathways and Interactions
Share to RNA Research and Splicing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23228155
DOI: 10.1186/1756-8722-5-74

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 9 closest

Alternative expression of TCRζ related genes in patients with chronic myeloid leukemiaPMID 23228155Read ↗

TCR<i>ζ</i>chain expression in T cells from patients with CMLSemantic proximity Read ↗

Alterations in the expression pattern of TCR zeta chain in T cells from patients with hematological diseases.Semantic proximity Read ↗

Molecular alterations in the TCR signaling pathway in patients with aplastic anemia.Semantic proximity Read ↗

Deficiency of CD3gamma, delta, epsilon, and zeta expression in T cells from AML patientsSemantic proximity Read ↗

DNA microarray gene expression profile of T cells with the splice variants of TCRzeta mRNA observed in systemic lupus erythematosus.Semantic proximity Read ↗

TCRzeta mRNA splice variant forms observed in the peripheral blood T cells from systemic lupus erythematosus patients.Semantic proximity Read ↗

Alternative Splicing Factor/Splicing Factor 2 Regulates the Expression of the ζ Subunit of the Human T Cell Receptor-associated CD3 ComplexSemantic proximity Read ↗

TCR zeta chain lacking exon 7 in two patients with systemic lupus erythematosusSemantic proximity Read ↗

Decreased Stability and Translation of T Cell Receptor ζ mRNA with an Alternatively Spliced 3′-Untranslated Region Contribute to ζ Chain Down-regulation in Patients with Systemic Lupus ErythematosusSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.