Article
Breast tumor copy number aberration phenotypes and genomic instability.
BMC cancer - 18 Apr 2006
Fridlyand Jane, Snijders Antoine M, Ylstra Bauke, Li Hua, Olshen Adam, Segraves Richard, Dairkee Shanaz, Tokuyasu Taku, Ljung Britt Marie, Jain Ajay N, McLennan Jane, Ziegler John, Chin Koei, Devries Sandy, Feiler Heidi, Gray Joe W, Waldman Frederic, Pinkel Daniel, Albertson Donna G
Abstract excerpt
BACKGROUND: Genomic DNA copy number aberrations are frequent in solid tumors, although the underlying causes of chromosomal instability in tumors remain obscure. Genes likely to have genomic instability phenotypes when mutated (e.g. those involved in mitosis, replication, repair, and telomeres) a...
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