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Article

Cre recombinase activity specific to postnatal, premeiotic male germ cells in transgenic mice

10 Oct 2008

Abstract excerpt

We have generated a transgenic mouse line,Tg(Stra8-cre)1Reb (Stra8-cre), which expresses improved Cre recombinase under the control of a 1.4 Kb promoter region of the germ cell-specific stimulated by retinoic acid gene 8 (Stra8). cre is expressed only in males beginning at postnatal day (P)3 in early-stage spermatogonia and is detected through preleptotene-stage spermatocytes. To further define when cre becomes...

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PMID: 18850594
DOI: 10.1002/dvg.20437

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