Article
miR-451 regulates zebrafish erythroid maturation in vivo via its target gata2.
Blood - 19 Feb 2009
Pase Luke, Layton Judith E, Kloosterman Wigard P, Carradice Duncan, Waterhouse Peter M, Lieschke Graham J
Abstract excerpt
We demonstrate that in zebrafish, the microRNA miR-451 plays a crucial role in promoting erythroid maturation, in part via its target transcript gata2. Zebrafish miR-144 and miR-451 are processed from a single precursor transcript selectively expressed in erythrocytes. In contrast to other hemato...
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