Article
The miR-144/451eGFP allele, a novel tool for resolving the erythroid potential of hematopoietic precursors.
Blood - 15 Sept 2011
Rasmussen Kasper D, O'Carroll Dónal
Abstract excerpt
A long outstanding problem is the resolution of the full potential of hematopoietic precursors. The commonly used allotypic marker Ly5 permits the tracing of lymphoid and granulocyte-macrophage (GM) output. Here we present a novel eGFP allele that allows the quantitative analysis of red blood cell (RBC) origin at the single-cell level. The miR-144/451 locus is required for erythroid development and homeostasis....
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