Article
Candidate EDA targets revealed by expression profiling of primary keratinocytes from Tabby mutant mice.
Gene - 31 Dec 2008
Esibizione Diana, Cui Chang-Yi, Schlessinger David
Abstract excerpt
EDA, the gene mutated in anhidrotic ectodermal dysplasia, encodes ectodysplasin, a TNF superfamily member that activates NF-kB mediated transcription. To identify EDA target genes, we have earlier used expression profiling to infer genes differentially expressed at various developmental time points in Tabby (Eda-deficient) compared to wild-type mouse skin. To increase the resolution to find genes whose expression...
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