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Article

Attenuation of Mammary Gland Dysplasia and Feeding Difficulties in Tabby Mice by Fetal Therapy.

Journal of mammary gland biology and neoplasia - 1 Sept 2018

Wahlbuhl Mandy, Schuepbach-Mallepell Sonia, Kowalczyk-Quintas Christine, Dick Angela, Fahlbusch Fabian B, Schneider Pascal, Schneider Holm

Abstract excerpt

Hypohidrotic ectodermal dysplasias (HED) are hereditary differentiation disorders of multiple ectodermal structures including the mammary gland. The X-linked form of HED (XLHED) is caused by a lack of the secreted signaling molecule ectodysplasin A1 (EDA1) which is encoded by the gene EDA and belongs to the tumor necrosis factor (TNF) superfamily. Although male patients (hemizygous) are usually more severely...

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Source

Identifiers

PMID: 29855766
DOI: 10.1007/s10911-018-9399-x

Genes

EDA
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Attenuation of Mammary Gland Dysplasia and Feeding Difficulties in Tabby Mice by Fetal Therapy.PMID 29855766Read ↗

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Candidate EDA targets revealed by expression profiling of primary keratinocytes from Tabby mutant mice.Semantic proximity Read ↗

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