Article
Apolipoprotein E genotype is related to nitric oxide production in platelets.
Cell biochemistry and function - 1 Dec 2008
Marcourakis Tania, Bahia Valéria S, Kawamoto Elisa M, Munhoz Carolina D, Gorjão Renata, Artes Rinaldo, Kok Fernando, Caramelli Paulo, Nitrini Ricardo, Curi Rui, Scavone Cristoforo
Abstract excerpt
The presence of the epsilon4 allele of apolipoprotein E (APOE) is considered a risk factor for sporadic Alzheimer's disease (AD). Our recent data demonstrated that the systemic modulation of oxidative stress in platelets and erythrocytes is disrupted in aging and AD. In this study, the relationsh...
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