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Article

A new binding assay of von Willebrand factor and glycoprotein Ib using solid-phase biotinylated platelets.

Journal of pharmacological sciences - 1 Oct 2008

Hayata Kenji, Nakayama Takayuki, Matsushita Tadashi, Sakano Katsuichi

Abstract excerpt

To obtain compounds that inhibit the interaction of von Willebrand factor (vWF) and glycoprotein (GP) Ib, a novel binding assay was established. The binding of fixed platelets to vWF-R497 mutant was quantified by a solid phase assay. In this assay, fixed platelets bound to the vWF-R497 mutant, ca...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18845909
DOI: 10.1254/jphs.08147sc

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18845909-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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