Article
Design and utility of temperature-sensitive Gal4 mutants for conditional gene expression in Drosophila.
Fly - 1 Jan 2000
Mondal Kajari, VijayRaghavan K, Varadarajan Raghavan
Abstract excerpt
Temperature-sensitive (ts) mutants are valuable tools to study the function of essential genes in vivo. Despite their widespread use, little is known about mechanisms responsible for the temperature-sensitive (ts) phenotype, or of the transferability of ts mutants of a specific gene between organisms. Since ts mutants are typically generated by random mutagenesis it is difficult to isolate such mutants without...
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