Article
MicroRNA-mediated up-regulation of an alternatively polyadenylated variant of the mouse cytoplasmic {beta}-actin gene.
Nucleic acids research - 1 Nov 2008
Ghosh Tanay, Soni Kartik, Scaria Vinod, Halimani Mahantappa, Bhattacharjee Chaitali, Pillai Beena
Abstract excerpt
Actin is a major cytoskeletal protein in eukaryotes. Recent studies suggest more diverse functional roles for this protein. Actin mRNA is known to be localized to neuronal synapses and undergoes rapid deadenylation during early developmental stages. However, its 3'-untranslated region (UTR) is not characterized and there are no experimentally determined polyadenylation (polyA) sites in actin mRNA. We have found...
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