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Article

Influence of CYP2D6*10 on the pharmacokinetics of metoprolol in healthy Korean volunteers.

Journal of clinical pharmacy and therapeutics - 1 Oct 2008

Jin S K, Chung H J, Chung M W, Kim J-I, Kang J-H, Woo S W, Bang S, Lee S H, Lee H J, Roh J

Abstract excerpt

BACKGROUND AND OBJECTIVE: Genetic polymorphism of CYP2D6 leads to differences in pharmacokinetics of CYP2D6 substrates. The CYP2D6*10 allele is clinically important in Koreans because of its high frequency in Asians. We investigated whether the pharmacokinetics of metoprolol was altered by the presence of the CYP2D6*10 allele in Korean subjects. METHODS: One hundred and seven volunteers were recruited and grouped...

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Source

Identifiers

PMID: 18834373
DOI: 10.1111/j.1365-2710.2008.00945.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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