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Article

Binding of complement inhibitor C4b-binding protein contributes to serum resistance of Porphyromonas gingivalis.

Journal of immunology (Baltimore, Md. : 1950) - 15 Oct 2008

Potempa Michal, Potempa Jan, Okroj Marcin, Popadiak Katarzyna, Eick Sigrun, Nguyen Ky-Anh, Riesbeck Kristian, Blom Anna M

Abstract excerpt

The periodontal pathogen Porphyromonas gingivalis is highly resistant to the bactericidal activity of human complement, which is present in the gingival crevicular fluid at 70% of serum concentration. All thirteen clinical and laboratory P. gingivalis strains tested were able to capture the human complement inhibitor C4b-binding protein (C4BP), which may contribute to their serum resistance. Accordingly, in serum...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18832711
DOI: 10.4049/jimmunol.181.8.5537
PMCID: PMC2602967

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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