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Article

Effect of inactivation of the Arg- and/or Lys-gingipain gene on selected virulence and physiological properties of Porphyromonas gingivalis.

Infection and immunity - 1 Aug 2003

Grenier Daniel, Roy Sophie, Chandad Fatiha, Plamondon Pascale, Yoshioka Masami, Nakayama Koji, Mayrand Denis

Abstract excerpt

Proteolytic enzymes produced by Porphyromonas gingivalis are thought to play critical roles in the pathogenesis of periodontitis. The aim of this study was to investigate the effect of gingipain cysteine proteinase gene inactivation on selected pathological and physiological functions of P. gingivalis. Our results showed that Arg- and Lys-gingipain activities are critical components for the efficient growth of P....

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Identifiers

PMID: 12874356
DOI: 10.1128/IAI.71.8.4742-4748.2003
PMCID: PMC166032

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Effect of inactivation of the Arg- and/or Lys-gingipain gene on selected virulence and physiological properties of Porphyromonas gingivalis.PMID 12874356Read ↗

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