Article
Porphyromonas gingivalis proteinases as virulence determinants in progression of periodontal diseases.
Journal of biochemistry - 1 Aug 2000
Kadowaki T, Nakayama K, Okamoto K, Abe N, Baba A, Shi Y, Ratnayake D B, Yamamoto K
Abstract excerpt
Porphyromonas gingivalis, one of the major causative agents of periodontal diseases, produces large amounts of arginine- and lysine-specific cysteine proteinases in cell-associated and secretory forms, which are now referred to as Arg-gingipain (Rgp) and Lys-gingipain (Kgp), respectively. A number of studies have revealed that these proteinases are closely associated with the periodontopathogenesis of this...
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