Article
Complement and periodontitis.
Biochemical pharmacology - 15 Dec 2010
Hajishengallis George
Abstract excerpt
Although the complement system is centrally involved in host defense, its overactivation or deregulation (e.g., due to inherent host genetic defects or due to pathogen subversion) may excessively amplify inflammation and contribute to immunopathology. Periodontitis is an oral infection-driven chronic inflammatory disease which exerts a systemic impact on health. This paper reviews evidence linking complement to...
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