Article
Involvement of a lysine-specific cysteine proteinase in hemoglobin adsorption and heme accumulation by Porphyromonas gingivalis.
The Journal of biological chemistry - 14 Aug 1998
Okamoto K, Nakayama K, Kadowaki T, Abe N, Ratnayake D B, Yamamoto K
Abstract excerpt
The oral anaerobic bacterium Porphyromonas gingivalis, a major pathogen of advanced adult periodontitis, produces a novel class of cysteine proteinases in both cell-associated and secretory forms. A lysine-specific cysteine proteinase (Lys-gingipain, KGP), as well as an arginine-specific cysteine...
Topics
- Adhesins, Bacterial
- Adsorption
- Base Sequence
- Cysteine Endopeptidases
- DNA Probes
- DNA, Bacterial
- Fibrinogen
- Gingipain Cysteine Endopeptidases
- Hemagglutination Tests
- Hemagglutinins
- Heme
- Hemoglobins
- Hydrolysis
- Lysine
- Mutation
- Porphyromonas gingivalis
- Receptors, Cell Surface