Article
Molecular characterization of the Aspergillus fumigatus NCS-1 homologue, NcsA.
Molecular genetics and genomics : MGG - 1 Dec 2008
Mota Júnior André Oliveira, Malavazi Iran, Soriani Frederico Marianetti, Heinekamp Thorsten, Jacobsen Ilse, Brakhage Axel A, Savoldi Marcela, Goldman Maria Helena S, da Silva Ferreira Márcia Eliana, Goldman Gustavo Henrique
Abstract excerpt
Here, we characterize the Aspergillus fumigatus homologue ncsA Neuronal Calcium Sensor. We showed that ncsA is not an essential gene and ncsA growth was decreased in the presence of EGTA and SDS. Furthermore, the ncsA mutant is more resistant to calcium chloride. NcsA:mRFP localizes to the cytoplasm and its cellular localization is not affected by the cellular response to either calcium chloride or EGTA. The ncsA...
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