Article
Fission yeast homolog of neuronal calcium sensor-1 (Ncs1p) regulates sporulation and confers calcium tolerance.
The Journal of biological chemistry - 26 Mar 2004
Hamasaki-Katagiri Nobuko, Molchanova Tatiana, Takeda Kazuyo, Ames James B
Abstract excerpt
The neuronal calcium sensor (NCS) proteins (e.g. recoverin, neurocalcins, and frequenin) are expressed at highest levels in excitable cells, and some of them regulate desensitization of G protein-coupled receptors. Here we present NMR analysis and genetic functional studies of an NCS homolog in fission yeast (Ncs1p). Ncs1p binds three Ca2+ ions at saturation with an apparent affinity of 2 microm and Hill...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
