Article
OSM-9 and OCR-2 TRPV channels are accessorial warm receptors in Caenorhabditis elegans temperature acclimatisation.
Scientific reports - 29 Oct 2020
Ohnishi Kohei, Saito Shigeru, Miura Toru, Ohta Akane, Tominaga Makoto, Sokabe Takaaki, Kuhara Atsushi
Abstract excerpt
Caenorhabditis elegans (C. elegans) exhibits cold tolerance and temperature acclimatisation regulated by a small number of head sensory neurons, such as the ADL temperature-sensing neurons that express three transient receptor potential vanilloid (TRPV) channel subunits, OSM-9, OCR-2, and OCR-1. Here, we show that an OSM-9/OCR-2 regulates temperature acclimatisation and acts as an accessorial warmth-sensing...
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