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Article

Caenorhabditis elegans TRPA-1 functions in mechanosensation.

Nature neuroscience - 1 May 2007

Kindt Katie S, Viswanath Veena, Macpherson Lindsey, Quast Kathleen, Hu Hongzhen, Patapoutian Ardem, Schafer William R

Abstract excerpt

Members of the transient receptor potential (TRP) ion channel family mediate diverse sensory transduction processes in both vertebrates and invertebrates. In particular, members of the TRPA subfamily have distinct thermosensory roles in Drosophila, and mammalian TRPA1 is postulated to have a function in noxious cold sensation and mechanosensation. Here we show that mutations in trpa-1, the C. elegans ortholog of...

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Source

Identifiers

PMID: 17450139
DOI: 10.1038/nn1886

Genes

TRPA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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