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Article

Proteomic analysis of scleroderma lesional skin reveals activated wound healing phenotype of epidermal cell layer.

Rheumatology (Oxford, England) - 1 Dec 2008

Aden N, Shiwen X, Aden D, Black C, Nuttall A, Denton C P, Leask A, Abraham D, Stratton R

Abstract excerpt

OBJECTIVE: To identify using proteomic analysis, proteins of altered abundance in the skin of patients with SSc. METHODS: 4 mm excision biopsies were obtained from the forearm involved skin of 12 diffuse SSc patients and 12 healthy controls. Two-dimensional gel electrophoresis was used to separate and define proteins in normal and SSc skin biopsy material. Proteins of altered abundance in the disease were...

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PMID: 18829709
DOI: 10.1093/rheumatology/ken370

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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