Article
Association between DLA-DRB1.2 allelic diversity and development of mammary gland tumors in dogs.
Acta veterinaria Scandinavica - 14 Nov 2019
Vahedi Seyed Milad, Nikbakht Gholamreza, Jamshidi Shahram, Lankarani Leila, Alimi Nika, Esmailnejad Atefeh
Abstract excerpt
BACKGROUND: The major histocompatibility complex (MHC) is the best-characterized genetic region related to resistance/susceptibility to a wide range of infectious and immune-mediated diseases. Evidences suggest that MHC class II genes may play an important role in developing different types of tumors including breast cancer. Canine mammary gland tumors (CMTs) are the most common neoplasms in female dogs. In the...
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