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Article

Genetic analysis of PALB2 gene WD40 domain in canine mammary tumour patients.

Veterinary medicine and science - 1 May 2024

Çıldır Özge Şebnem, Özmen Özge, Kul Selim, Rişvanlı Ali, Özalp Gözde, Sabuncu Ahmet, Kul Oğuz

Abstract excerpt

BACKGROUND: DNA repair mechanisms are essential for tumorigenesis and disruption of HR mechanism is an important predisposing factor of human breast cancers (BC). PALB2 is an important part of the HR. There are similarities between canine mammary tumours (CMT) and BCs. As its human counterpart, PALB2 mutations could be a predisposing factor of CMT. OBJECTIVES: In this study, we aimed to investigate the impacts of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fanconi Anemia Complementation Group N Protein

Share to Genetic Predisposition to Disease

Share to Mammary Neoplasms, Animal

Share to Tumor Suppressor Proteins

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Identifiers

PMID: 38527110
DOI: 10.1002/vms3.1366
PMCID: PMC10962921

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