Article
Phenotypic and functional characterization of CD8(+) T regulatory cells.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2011
Ménoret Séverine, Guillonneau Carole, Bezié Séverine, Caron Lise, Anegon Ignacio, Li Xian-Liang
Abstract excerpt
Increasing evidence shows the presence and significance of CD8+ T regulatory cells (CD8+ Tregs) in both human and rodent transplant recipients, as well as in autoimmune disease models. We, hereafter, review all available data on the phenotypic and functional characterization of CD8+ Tregs, and we also provide detailed protocols to purify them and analyze their suppressive function. Different subsets of dendritic...
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