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Article

Structural basis for toxin resistance of beta4-associated calcium-activated potassium (BK) channels.

The Journal of biological chemistry - 29 Aug 2008

Gan Geliang, Yi Hong, Chen Maorong, Sun Liang, Li Wenxin, Wu Yingliang, Ding Jiuping

Abstract excerpt

The functional diversity of large conductance Ca(2+)- and voltage-dependent K(+) (BK) channels arises mainly from co-assembly of the pore-forming mSlo alpha subunits with four tissue-enriched auxiliary beta subunits. The structural basis of the interaction between alpha subunits with beta subunits is not well understood. Using computational and experimental methods, we demonstrated that four mSlo turrets...

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Identifiers

PMID: 18559348
DOI: 10.1074/jbc.M800179200
PMCID: PMC3259794

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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