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Article

Parathyroid-specific interaction of the calcium-sensing receptor and G alpha q.

Kidney international - 1 Dec 2008

Pi Min, Chen Ling, Huang MinZhao, Luo Qiang, Quarles L Darryl

Abstract excerpt

The calcium-sensing receptor regulates various parathyroid gland functions, including hormone secretion, gene transcription, and chief cell hyperplasia through G alpha q- and G alpha i-dependent signaling pathways. To determine the specific function of G alpha q in these processes, we generated transgenic mice using the human parathyroid hormone promoter to drive overexpression of a dominant negative G alpha q...

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Share to GTP-Binding Protein alpha Subunits, Gq-G11
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18813283
DOI: 10.1038/ki.2008.411
PMCID: PMC2760404

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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