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Article

Dual roles for NFAT transcription factor genes as oncogenes and tumor suppressors.

Molecular and cellular biology - 1 Dec 2008

Robbs Bruno K, Cruz Andre L S, Werneck Miriam B F, Mognol Giuliana P, Viola João P B

Abstract excerpt

Nuclear factor of activated T cells (NFAT) was first described as an activation and differentiation transcription factor in lymphocytes. Several in vitro studies suggest that NFAT family members are redundant proteins. However, analysis of mice deficient for NFAT proteins suggested different roles for the NFAT family of transcription factors in the regulation of cell proliferation and apoptosis. NFAT may also...

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Source

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Identifiers

PMID: 18809576
DOI: 10.1128/MCB.00256-08
PMCID: PMC2593389

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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