Article
Interplay of acute and persistent infections caused by Venezuelan equine encephalitis virus encoding mutated capsid protein.
Journal of virology - 1 Oct 2010
Atasheva Svetlana, Krendelchtchikova Valentina, Liopo Anton, Frolova Elena, Frolov Ilya
Abstract excerpt
Venezuelan equine encephalitis virus (VEEV) is a significant human and animal pathogen. The highlight of VEEV replication in vitro, in cells of vertebrate origin, is the rapid development of cytopathic effect (CPE), which is strongly dependent upon the expression of viral capsid protein. Besides being an integral part of virions, the latter protein is capable of (i) binding both the nuclear import and nuclear...
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