Article
p53 codon 72 proline/arginine polymorphism and autoimmune thyroid diseases.
Journal of clinical laboratory analysis - 1 Jan 2008
Chen Rong-Hsing, Chang Chwen-Tzuei, Wang Tzu-Yuan, Huang Wen-Liang, Tsai Chang-Hai, Tsai Fuu-Jen
Abstract excerpt
p53 protein participates in the processes of apoptosis, which is involved in a number of immunological reactions. In order to test whether the p53 gene could be used as a genetic marker for the prediction of the development of autoimmune thyroid diseases (AITD), we screened, by using polymerase chain reaction (PCR) analysis, for the C (CCC)/G (CGC) polymorphism at the p53 codon 72 (Pro 72/Arg 72) to determine the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
