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The TP53 codon 72 polymorphism and predisposition to adrenocortical cancer in Polish patients.

Oncology reports - 1 Jul 2006

Ignaszak-Szczepaniak Magdalena, Horst-Sikorska Wanda, Sawicka Joanna, Kaczmarek Marta, Slomski Ryszard

Abstract excerpt

The TP53 polymorphism occurs at codon 72 of exon 4 with two alleles encoding either arginine or proline. The association between this common polymorphism and risk of different cancers has been extensive studied, however various reports are controversial. We have analyzed the 72Pro polymorphic variant in patients with adrenocortical tumors to evaluate whether 72G--> C substitution at codon 72 of TP53 gene may be...

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PMID: 16786124

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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