Article
Inherited pelvic organ prolapse in the mouse: preliminary evaluation of a new murine model.
International urogynecology journal and pelvic floor dysfunction - 1 Jan 2009
McNanley Anna R, Johnson Aimee M, Flynn Michael K, Wood Ronald W, Kennedy Scott D, Reeder Jay E
Abstract excerpt
The objective of this study was to report the initial anatomic, radiographic, and genetic evaluations of a novel form of spontaneous pelvic organ prolapse (S-POP) in mice. We observed S-POP in a colony of UPII-SV40T transgenic mice developed for studies on bladder cancer. We utilized magnetic resonance imaging and necropsy to characterize this finding. We have established a breeding colony to identify inheritance...
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