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Article

Radiation cystitis modeling: A comparative study of bladder fibrosis radio-sensitivity in C57BL/6, C3H, and BALB/c mice.

Physiological reports - 1 Feb 2020

Zwaans Bernadette M M, Wegner Kyle A, Bartolone Sarah N, Vezina Chad M, Chancellor Michael B, Lamb Laura E

Abstract excerpt

A subset of patients receiving radiation therapy for pelvic cancer develop radiation cystitis, a complication characterized by mucosal cell death, inflammation, hematuria, and bladder fibrosis. Radiation cystitis can reduce bladder capacity, cause incontinence, and impair voiding function so severely that patients require surgical intervention. Factors influencing onset and severity of radiation cystitis are not...

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Identifiers

PMID: 32109348
DOI: 10.14814/phy2.14377
PMCID: PMC7048381

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