Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

P2RX7 Gln460Arg polymorphism is associated with depression among diabetic patients.

Progress in neuro-psychopharmacology & biological psychiatry - 12 Dec 2008

Nagy Geza, Ronai Zsolt, Somogyi Aniko, Sasvari-Szekely Maria, Rahman Omar Abdul, Mate Attila, Varga Timea, Nemoda Zsofia

Abstract excerpt

AIMS: Both diabetes mellitus and major depression are public health concerns, and the co-occurrence of these illnesses is highly frequent. Acting as a potential risk factor, hyperglycemia might facilitate the manifestation of depression in patients genetically predisposed to affective disorders. In the present study, candidate polymorphisms of the serotonin transporter, the tryptophan hydroxylase 2 (TPH2) genes,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain-Derived Neurotrophic Factor
Share to Depression

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Complications

Share to Glutamine

Share to Receptors, Purinergic P2

Share to Receptors, Purinergic P2X7

Share to Serotonin Plasma Membrane Transport Proteins

Share to Tryptophan Hydroxylase

Source

Identifiers

PMID: 18801407
DOI: 10.1016/j.pnpbp.2008.08.021

Genes

TPH2
BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

P2RX7 Gln460Arg polymorphism is associated with depression among diabetic patients.PMID 18801407Read ↗

Association between depression and the Gln460Arg polymorphism of P2RX7 gene: a dimensional approach.Semantic proximity Read ↗

The P2RX7 polymorphism rs2230912 is associated with depression: A meta-analysis.Semantic proximity Read ↗

P2X7 Receptor: A Potential Therapeutic Target for Depression?Semantic proximity Read ↗

Associations between depression severity and purinergic receptor P2RX7 gene polymorphisms.Semantic proximity Read ↗

P2RX7 gene is associated consistently with mood disorders and predicts clinical outcome in three clinical cohorts.Semantic proximity Read ↗

P2RX7, a gene coding for a purinergic ligand-gated ion channel, is associated with major depressive disorder.Semantic proximity Read ↗

Association between serotonin transporter promoter polymorphisms and psychological distress in a diabetic population.Semantic proximity Read ↗

The serotonin transporter promoter polymorphism (5-HTTLPR) is associated with type 2 diabetes.Semantic proximity Read ↗

Functional Val66Met polymorphism of Brain-derived neurotrophic factor in type 2 diabetes with depression in Han Chinese subjects.Semantic proximity Read ↗

Lack of association of P2RX7 gene rs2230912 polymorphism with mood disorders: a meta-analysis.Semantic proximity Read ↗

The role of purinergic signaling in depressive disorders.Semantic proximity Read ↗

Genetic association analysis of serotonin transporter polymorphism (5-HTTLPR) with type 2 diabetes patients of Pakistani population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.