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Article

Functional Val66Met polymorphism of Brain-derived neurotrophic factor in type 2 diabetes with depression in Han Chinese subjects.

Behavioral and brain functions : BBF - 22 Aug 2013

Zhou Jian-Xin, Li He-Chao, Bai Xue-Jun, Chang Bao-Cheng, Li Chun-Jun, Sun Pei, Chen Li-Ming

Abstract excerpt

BACKGROUND: Brain-derived neurotrophic factor (BDNF) has been implicated in the pathogenesis of major depression. Individuals with type 2 diabetes (T2DM) have a high prevalence of major depression and low levels of BDNF. We therefore explored whether the BDNF Val66Met polymorphism is associated with co-morbid depression and whether depression affects the serum levels of BDNF in a Han Chinese subjects with T2DM....

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Identifiers

PMID: 23968401
DOI: 10.1186/1744-9081-9-34
PMCID: PMC3765870

Genes

BDNF

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