Article
The serotonin transporter promoter polymorphism (5-HTTLPR) is associated with type 2 diabetes.
Clinica chimica acta; international journal of clinical chemistry - 1 Feb 2010
Iordanidou Maria, Tavridou Anna, Petridis Ioannis, Arvanitidis Kostas I, Christakidis Dimitrios, Vargemezis Vassilios, Manolopoulos Vangelis G
Abstract excerpt
BACKGROUND: The serotonergic system contributes substantially to the regulation of glucose homeostasis and feeding. 5-HTTLPR is a serotonin transporter (5-HTT) gene-linked polymorphic region that regulates the transcriptional activity of 5-HTT. Our aim was to investigate the possible association of 5-HTTLPR polymorphism with type 2 diabetes mellitus and obesity. METHODS: Study population consisted of 252 subjects...
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