Article
Genetic variants on apolipoprotein gene cluster influence triglycerides with a risk of coronary artery disease among Indians.
Molecular biology reports - 1 Jan 2010
AshokKumar Manickaraj, Subhashini Navaneethan Gnana Veera, SaiBabu Ramineni, Ramesh Arabandi, Cherian Kotturathu Mammen, Emmanuel Cyril
Abstract excerpt
Apolipoprotein C3 and apolipoprotien A5 are proteins coded from the APOA1/C3/A4/A5 gene cluster. Sst I polymorphism on apolipoprotein C3 and -1131C polymorphism of apolipoprotien A5 are key variants involved in triglyceride metabolism and cause a significant cardio-metabolic risk. Here, we have evaluated these two variants for their roles in coronary artery disease in patients of the Indian population. The...
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