Article
Effects of the XRCC1 gene-environment interactions on DNA damage in healthy Japanese workers.
Environmental and molecular mutagenesis - 1 Dec 2008
Weng Zuquan, Lu Yuquan, Weng Huachuan, Morimoto Kanehisa
Abstract excerpt
X-ray repair crosscomplementing group 1 (XRCC1) has a central role in base excision repair (BER) and single-strand break repair (SSBR). XRCC1 gene polymorphisms (codons 194, 280, and 399) have been identified, and in some cases have been reported to contribute to variations in DNA repair capacity and susceptibility to cancer. To further characterize the effects of XRCC1 gene polymorphisms and their possible...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
