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Article

Characterization of the p53 response to oncogene-induced senescence.

PloS one - 18 Sept 2008

Ruiz Lidia, Traskine Magali, Ferrer Irene, Castro Estrella, Leal Juan F M, Kaufman Marcelline, Carnero Amancio

Abstract excerpt

BACKGROUND: P53 activation can trigger various outcomes, among them reversible growth arrest or cellular senescence. It is a live debate whether these outcomes are influenced by quantitative or qualitative mechanisms. Furthermore, the relative contribution of p53 to Ras-induced senescence is also matter of controversy. METHODOLOGY/PRINCIPAL FINDINGS: This study compared situations in which different signals drove...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18800172
DOI: 10.1371/journal.pone.0003230
PMCID: PMC2535567

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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