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Article

Lamin A/C mutations in dilated cardiomyopathy.

Cardiology journal - 1 Jan 2014

Tesson Frédérique, Saj Michal, Uvaize Musfira Mohamed, Nicolas Hannah, Płoski Rafał, Bilińska Zofia

Abstract excerpt

Dilated cardiomyopathy (DCM) is one of the leading causes of heart failure and heart transplant. Mutations in 60 genes have been associated with DCM. Approximately 6% of all DCM cases are caused by mutations in the lamin A/C gene (LMNA). LMNA codes for type-V intermediate filaments that support the structure of the nuclear membrane and are involved in chromatin structure and gene expression. Most LMNA mutations...

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Source

Identifiers

PMID: 24846508
DOI: 10.5603/CJ.a2014.0037

Genes

LMNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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