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Article

Identification of novel mutations in LMNA associated with familial forms of dilated cardiomyopathy.

Genetic testing and molecular biomarkers - 1 Jun 2012

Stallmeyer Birgit, Koopmann Matthias, Schulze-Bahr Eric

Abstract excerpt

The lamin A/C proteins are major structural and functional components of the nuclear lamina. Mutations identified in LMNA encoding lamin A/C belong to the most frequently described causes for inherited forms of dilated cardiomyopathy (DCM). To elucidate the clinical characteristics of LMNA mutation carriers we performed genetic analysis of LMNA in 20 unrelated patients with DCM and cardiac conduction disease. In...

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Topics

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Share to Arrhythmias, Cardiac
Share to Cardiomyopathy, Dilated

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Mutational Analysis

Share to Heterozygote

Share to Lamin Type A

Share to Muscular Dystrophies

Share to Mutation, Missense

Source

Identifiers

PMID: 22224630
DOI: 10.1089/gtmb.2011.0214

Genes

LMNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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