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Article

Beta-1-adrenoceptor genetic variants and ethnicity independently affect response to beta-blockade.

Pharmacogenetics and genomics - 1 Oct 2008

Kurnik Daniel, Li Chun, Sofowora Gbenga G, Friedman Eitan A, Muszkat Mordechai, Xie Hong-Guang, Harris Paul A, Williams Scott M, Nair Usha B, Wood Alastair J J, Stein C Michael

Abstract excerpt

OBJECTIVES: Black patients may be less responsive to beta-blockers than whites. Genetic variants in the beta1-adrenergic receptor (beta1-AR) associated with lesser response to beta-blockers are more common in blacks than in whites. The purpose of this study was to determine whether ethnic differences in response to beta-blockade can be explained by differing distributions of functional genetic variants in the...

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Share to Adrenergic beta-Antagonists
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18794726
DOI: 10.1097/FPC.0b013e328309733f
PMCID: PMC2757009

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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