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Article

Tentacle probe sandwich assay in porous polymer monolith improves specificity, sensitivity and kinetics.

Nucleic acids research - 1 Nov 2008

Satterfield Brent C, Caplan Michael R, West Jay A A

Abstract excerpt

Nucleic acid sandwich assays improve low-density array analysis through the addition of a capture probe and a specific label, increasing specificity and sensitivity. Here, we employ photo-initiated porous polymer monolith (PPM) as a high-surface area substrate for sandwich assay analysis. PPMs are shown to enhance extraction efficiency by 20-fold from 2 microl of sample. We further compare the performance of...

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Identifiers

PMID: 18790801
DOI: 10.1093/nar/gkn564
PMCID: PMC2577359

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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