Article
A mixed film composed of oligonucleotides and poly(2-hydroxyethyl methacrylate) brushes to enhance selectivity for detection of single nucleotide polymorphisms.
Analytica chimica acta - 19 Feb 2010
Wong April K Y, Marushchak Denys O, Gradinaru Claudiu C, Krull Ulrich J
Abstract excerpt
Preliminary studies of mixed films composed of oligonucleotides and poly(2-hydroxyethyl methacrylate) (PHEMA) have recently been shown to enhance the selectivity for detection of 3 base-pair mismatched (3 bpm) oligonucleotide targets. Evaluation of selectivity for detection of single nucleotide p...
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