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Human Alveolar Macrophage Gene Responses to <i>Mycobacterium tuberculosis</i> Strains H37Ra and H37Rv

11 Sept 2008

Abstract excerpt

H37Rv and H37Ra have been widely used as models of virulent and avirulent strains, respectively, of Mycobacterium tuberculosis. Since the sequencing of H37Rv, microarrays have been used to investigate gene expression of M. tuberculosis strains under various conditions, and to compare gene expression of specific isolates of the organism. Because differences in the virulence of these organisms could also be...

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PMID: 18787177
DOI: 10.1165/rcmb.2008-0219oc

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