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Gene Expression and Antimicrobial Activity of Bovine Macrophages in Response to <i>Mycobacterium avium</i> subsp. <i>paratuberculosis</i>

1 Jul 2004

Abstract excerpt

We evaluated gene expression and antimicrobial responses of bovine monocyte-derived macrophages incubated with Mycobacterium avium subsp. paratuberculosis (M. a. ptb), the causative agent of Johne's disease. Gene expression was evaluated by the use of human noncompetitive high-density oligonucleotide microarrays. Bovine messenger RNA hybridized with 14.2-18.2% of the 12,600 oligonucleotide probe sets. When...

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PMID: 15232132
DOI: 10.1354/vp.41-4-326

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